In a city of mostly Victorian hotels, Vitale boasts a new building by architects Heller Manus, its striking brick-and-glass corner tower gleaming over Ferry Plaza and the Embarcadero. The Zen-modern interior, with its lean settees, wooden paneling, and limestone baths, is elegantly spare and soothing, suited to the hotel’s spa-like focus on revitalization. Rooms that look onto the Bay Bridge and Yerba Buena Island are pricey, but the rooftop views are magnificent at sunset—and free.